Raised in New York City, Anastacia came from an entertainment oriented
family: her father was a singer; her mother an actress in musical theater on Broadway. Despite being diagnosed with the chronic intestinal illness Crohn's disease at age 13, she developed a career as a dancer, appearing on Club MTV and in such music videos as Salt-N-Pepa's "Everybody Get Up" and "Twist and Shout."
In 1999, she was a finalist on the MTV talent contest show The Cut, which attracted the interest of record labels. She signed to the Daylight custom label of Sony Music's Epic Records and recorded her debut album, Not That Kind, which was released internationally in 2000. The result was massive success: the album reached the Top Ten in eight European and Far East
countries, selling over two million copies. At home, the single "I'm Outta Love" became a dance hit, paving the way for the release of a revised version of Not That Kind in the U.S. in 2001.
Having taken time off from the music business to recover from breast cancer, this multi-platinum artist decided to make her come back at the Cape Town 46664 event. She sang with U2 and Queen, and also contributed to the song "Amandla", recording the song and providing some of the
lyrics.